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Interstitial point radiance spectroscopy of turbid media
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10.1063/1.3116132
/content/aip/journal/jap/105/10/10.1063/1.3116132
http://aip.metastore.ingenta.com/content/aip/journal/jap/105/10/10.1063/1.3116132
View: Figures

Figures

Image of FIG. 1.
FIG. 1.

Radiance geometry for a point source in a turbid optical medium of infinite extent.

Image of FIG. 2.
FIG. 2.

Representative fits of simulated relative (a) point fluence and (b) point radiance at various oxygen saturations (0–1 in increments of 0.25) at a fixed of . Crosses are the forward generated spectra while the solid lines are the resulting fits. The fluence spectra were generated under noise-free conditions with no water, while the radiance spectra were generated with 1% added noise and with the added presence of water (100% concentration).

Image of FIG. 3.
FIG. 3.

Best fit (a) , (b) , (c) , and (d) obtained by fitting relative point fluence spectra (normalized to 700 nm) as a function of hemoglobin concentration [(a), (b), and (d)] or (c) used to create the simulated data. Solid lines indicate perfect agreement.

Image of FIG. 4.
FIG. 4.

Best fit (a) , (b) , (c) , and (d) obtained by fitting relative point radiance ratio spectra, , as a function of hemoglobin concentration [(a), (b), and (d)] or (c) used to create the simulated data. Solid lines indicate perfect agreement.

Image of FIG. 5.
FIG. 5.

Best fit obtained by fitting (a) relative point fluence (normalized to 700 nm) and (b) relative point radiance ratio spectra, , as a function of used to create the simulated data. Solid lines indicate perfect agreement.

Image of FIG. 6.
FIG. 6.

Typical (a) point radiance ratio [Eq. (2)] and (b) normalized [ from Eq. (4)] measured at 7.5 mm in an intralipid phantom as aliquots of naphthol green dye are added. The solid lines indicate the best fits of the P3 approximation for and to each spectrum. (c) Best fit (left -axis) and dye concentration (right -axis) determined by simultaneously fitting , , and spectra acquired from intralipid phantoms with different concentrations of naphthol green dye. The dashed lines denote the theoretically expected result. Error bars are the recovered properties assuming ±0.5 mm positioning error during fitting.

Image of FIG. 7.
FIG. 7.

Typical (a) point radiance ratio [Eq. (2)] and (b) normalized [ from Eq. (4)] measured at 7.5 mm in an intralipid phantom as aliquots of additional intralipid are added. The solid lines indicate the best fits of the P3 approximation for and to each spectrum. (c) Best fit (left -axis) and dye concentration (right -axis) determined by simultaneously fitting , , and spectra acquired in intralipid phantoms of different concentrations. The dashed line shows the values as predicted by Jacques (Ref. 14).

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/content/aip/journal/jap/105/10/10.1063/1.3116132
2009-05-19
2014-04-19
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Interstitial point radiance spectroscopy of turbid media
http://aip.metastore.ingenta.com/content/aip/journal/jap/105/10/10.1063/1.3116132
10.1063/1.3116132
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