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Photoluminescence model for a hybrid aptamer-GaAs optical biosensor
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10.1063/1.3419714
/content/aip/journal/jap/107/10/10.1063/1.3419714
http://aip.metastore.ingenta.com/content/aip/journal/jap/107/10/10.1063/1.3419714

Figures

Image of FIG. 1.
FIG. 1.

Room temperature PL spectra of the T10ATP aptamer-treated GaAs samples as well as that of an untreated substrate: (a) following the initial probe functionalization and (b) after exposure to the ATP or GTP solution.

Image of FIG. 2.
FIG. 2.

Schematic representation of the proposed mechanism responsible for the biorecognition-facilitated change in the GaAs luminescence: (a) prior to the target sensing and (b) after the binding of the target ATP ligands.

Image of FIG. 3.
FIG. 3.

PL spectra of GaAs substrates modified with thiolated T10ATP, nonthiolated T10ATP, as well as that of an untreated substrate.

Image of FIG. 4.
FIG. 4.

A comparison of room temperature PL spectra of an ATP-treated T10ATP sample before and after dissociation (denoted as and -ATP, respectively), a T10ATP sample, and an untreated GaAs substrate.

Image of FIG. 5.
FIG. 5.

Relative change in the peak PL intensity of the oligonucleotide-modified GaAs samples as a function of the aptamer probe length: (a) PL yield of the aptamer functionalized sample relative to that of an untreated substrate, (b) PL yield of the aptamer functionalized sample relative to that exposed to the ATP assay solution. The data reflect the natural logarithm of the specified PL ratios divided by the GaAs absorption coefficient, (experimental data: ●, model fit: – – –). The error bars correspond to the standard deviation in the PL measurements obtained at three different locations on the surface of each sample.

Tables

Generic image for table
Table I.

Sequences of the oligonucleotide aptamer probes.

Generic image for table
Table II.

Material parameters used in the modeling computation.

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/content/aip/journal/jap/107/10/10.1063/1.3419714
2010-05-25
2014-04-24
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Photoluminescence model for a hybrid aptamer-GaAs optical biosensor
http://aip.metastore.ingenta.com/content/aip/journal/jap/107/10/10.1063/1.3419714
10.1063/1.3419714
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