Instruction of physical mechanism of IMR assay. (a) The ac susceptibility generated with the individual biofunctionalized magnetic nanoparticles in magnetic reagent, and (b) the ac susceptibility of the magnetic reagent after the association between biofunctionalized magnetic nanoparticles and biotargets.
Scheme of the four-channel SQUID-based ac magnetosuscptometry.
Frequency dependent shielding factor of the magnetically shielded box is shape of cylinder used in the SQUID-based magnetosusceptometry shown in Fig. 2.
Real-time signals (i.e., curve) of four identical magnetic reagents mixed with four identical 100 ng/ml NEGF solution. Each curve is probed with one channel of the four-channel SQUID-based magnetosusceptometry shown in Fig. 2.
IMR signal as a function of the concentration of VEGF . The data points are fitted to logistic function expressed as Eq. (3).
Scaling feature for the characteristic curves of IMR assays on proteins (VEGF), viruses (H5N1), and cytokines .
Resistance and inductance of excitation coils and pick-up coil used in the multichannel SQUID-based magneosusceptometry schematically shown in Fig. 2.
Detected mean value of concentration , standard deviation of measured concentration , and the CV from triple tests, and the error (%) via Eq. (4) for each spiked concentration .
Article metrics loading...
Full text loading...