Illustrations for (a) associations between AFP molecule and functionalized magnetic nanoparticles via different epitopes and (b) mixture of anti-AFP-functionalized magnetic nanoparticles and dextran-coated magnetic nanoparticles.
AFP concentration dependent IMR signals for various Mbio-part's. The solid lines denote the fitting curves via Eq. (1) . AFP concentration in unit of ng/ml is converted to numbers of AFP molecule. The molecular weight of AFP is 816 000 g/mol. The volume of AFP solution used is 60 μl.
Fitting parameter γ in Eq. (1) as a function of Mbio-part.
IMR signals at the AFP concentration 1000 ng/ml for various Mbio-part's.
IMR signals for various Mbio-part's using pH-7.2 PBS solution as a to-be-detected sample.
Values for the fitting parameters A, B, ϕo, and γ in Eq. (1) for various Mbio's.
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