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Molecule-assisted nanoparticle clustering effect in immunomagnetic reduction assay
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10.1063/1.4800536
/content/aip/journal/jap/113/14/10.1063/1.4800536
http://aip.metastore.ingenta.com/content/aip/journal/jap/113/14/10.1063/1.4800536

Figures

Image of FIG. 1.
FIG. 1.

Illustrations for (a) associations between AFP molecule and functionalized magnetic nanoparticles via different epitopes and (b) mixture of anti-AFP-functionalized magnetic nanoparticles and dextran-coated magnetic nanoparticles.

Image of FIG. 2.
FIG. 2.

AFP concentration dependent IMR signals for various Mbio-part's. The solid lines denote the fitting curves via Eq. (1) . AFP concentration in unit of ng/ml is converted to numbers of AFP molecule. The molecular weight of AFP is 816 000 g/mol. The volume of AFP solution used is 60 μl.

Image of FIG. 3.
FIG. 3.

Fitting parameter γ in Eq. (1) as a function of Mbio-part.

Image of FIG. 4.
FIG. 4.

IMR signals at the AFP concentration 1000 ng/ml for various Mbio-part's.

Image of FIG. 5.
FIG. 5.

IMR signals for various Mbio-part's using pH-7.2 PBS solution as a to-be-detected sample.

Tables

Generic image for table
Table I.

Values for the fitting parameters A, B, ϕo, and γ in Eq. (1) for various Mbio's.

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/content/aip/journal/jap/113/14/10.1063/1.4800536
2013-04-10
2014-04-25
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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Molecule-assisted nanoparticle clustering effect in immunomagnetic reduction assay
http://aip.metastore.ingenta.com/content/aip/journal/jap/113/14/10.1063/1.4800536
10.1063/1.4800536
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