Schematic figure of a magnetic nanoparticle and its analytical model.
Schematic figure of the preparation of magnetically fractionated MNPs (MS1, MS2, and MS3) from Ferucarubotran.
Harmonic spectra of the immobilized MS series when an AC excitation field with frequency of 10 kHz is applied. The amplitude of the field is (a) μ 0 H ac1 = 2.8 mT and (b) μ 0 H ac2 = 28 mT.
Static M-H curve for each MS series.
(a) Estimated distribution of the effective core size for each MS series. The vertical axis represents volume weighted number density of the MNPs. (b) Solid line represents the reconstructed core size distribution of Ferucarbotran, which was calculated from those of the MS series shown in Fig. 5(a) . Dotted line represents the effective core size distribution of Resovist®.
Estimated correlations between the anisotropy energy barrier E B and magnetic moment m for the MS series. Dotted and dashed-dotted lines represent the relationship for the case of K = 3 kJ/m3 and 4 kJ/m3 in Eq. (4) , respectively. M s was set to 360 kA/m.
Hydrodynamic size distribution of each MS series measured with DLS. The vertical axis represents the volume weighted number density of the MNPs.
Relationship between the mean core size d cp and the mean hydrodynamic size d hp for the MS series.
Comparison between experimental harmonic spectra and corresponding numerical simulations from MS series when an AC excitation field with μ 0 H ac2 = 28 mT and f = 10 kHz is applied.
Harmonic signal strength generated by each effective core size distributed in (a) MS1, (b) MS2, and (c) MS3.
Parameters of the MS series, which were magnetically divided into three fractions from Ferucarbotran. The peak effective core size d cp and peak hydrodynamic size d hp were determined from Figs. 5(a) and 7 , respectively. The thickness of the coating material t co is calculated with t co = (d hp – d cp)/2.
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