banner image
No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
Stochastic chemical reactions in microdomains
Rent this article for
View: Figures


Image of FIG. 1.
FIG. 1.

Chemical reaction inside a microdomain. Each free particle (white circle) moves according to a Brownian motion until it binds to a free site (black color). An occupied site cannot accept any other particles. A molecule is composed of a finite number of sites. Parts of the microdomain is reflective and the rest is absorbing.

Image of FIG. 2.
FIG. 2.

Schematic reaction in a microdomain where channels are located on the boundary. Molecules move according to a Brownian motion inside the domain. When a particle hits a free channel, it can bound and stays there for a certain amount of time. Particles can escape through the absorbing boundary.

Image of FIG. 3.
FIG. 3.

Normalized variance , for , 1, 2, 4.

Image of FIG. 4.
FIG. 4.

The variance square equal to , for various values of the backward binding rate . The total number of substrate molecules is fixed at and .

Image of FIG. 5.
FIG. 5.

Experimental analysis of the fluctuation in the number of open channel. The left panel corresponds to the current response for various concentration of the gating molecules (cGMP), in a detached patch experiment of a cone photoreceptors membrane. On the right panel, the variance is plotted vs the mean current, which is proportional to the number of gating molecules (cGMP). This picture was published in Ref. 4 (Fig. 2).


Article metrics loading...


Full text loading...

This is a required field
Please enter a valid email address
752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Stochastic chemical reactions in microdomains