All possible conformations of a polymer of segments during translocation. and are defined as the number of segments inside the channel and the receptor compartment, respectively.
The free energy profiles of translocation of a chain with length and donor compartment radius . The translocation coordinate denotes the number of segments inside the receptor compartment. The various free energy labels in (a) are defined in Eqs. (2.12), (2.13), (3.9), (3.10), and (2.20)–(2.22). (a) , , and . (b) , , and . (c) , , and . (d) , , and .
The free energy barrier of channel filling as a function of different parameters. (a) , , and . (b) , , and . (c) , , , and . (d) , , , and .
Total translocation time . (a) , , . Solid lines: , 40, 50, and 60. Dotted line: for . Dashed line: for . (b) , , , , 40, 50, and 60. (c) , , , , 4, 5, and 6. (d) , , , , 4, and 5.
Translocation time distribution of for , 4, 5, respectively. , , , and .
(a) Free energy profiles of translocation involve crossing a free energy barrier [step (1)] and an arbitrary profile [step (2)]. The corresponding correction factors to (in the limits explained in the text) are (b) , (c) , (d) , (e) , and (f) .
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