Typical snapshots of the probed DNA in the solutions containing unprobed DNA at with various salt concentrations. (a) A random coiled DNA at , (b) a globular DNA at , and (c) an elongated DNA at . (d)–(f) show illustrations of (a)–(c).
The average dimension of DNA plotted against the salt concentration for the solutions containing (a) PEG6000 and (b) PEG20000. Filled circles, filled triangles, and open circles represent random coiled, globular, and elongated DNA, respectively.
Distribution of the DNA dimension at various DNA concentrations (indicated in the figure) for the solutions containing (a) PEG6000 and (b) PEG20000.
Illustration of microscopic structures for globular DNAs and DNA aggregates considered in the free energy model.
The total free energy per chain in the presence of PEG6000 as a function of the distance between DNA segments for (a) globular DNA (isolated) and (b) elongated DNA (in the aggregate) for various Debye lengths . Horizontal broken line shows the free energy of random coiled DNA for comparison.
The steady state solutions of and plotted against . Bold, dotted, broken, and thin lines indicate the solutions for , 2/3, 1/3, and 0, respectively.
The number fraction of DNA globules and aggregates plotted against the DNA concentration . Filled and unfilled symbols are experimental values of and for PEG6000 (circles) and PEG 20000 (triangles), respectively. Solid and broken curves are the steady state solution for and obtained by the kinetic model at for PEG6000 (thin curves) and PEG20000 (bold curves).
Illustration of the model for the depletion interaction. Gray circles represent cylinders (DNAs) and the dark gray represents the depletion region.
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