Trajectory snapshots of order parameter (a) and concentration field (b) for the DOPC:SM:CHOL concentration 35:40:25. CHOLs are visible as small black segments representing the two-dimensional rods. Color codes are in (c) and (d).
Distributions of order parameter (a) and concentration field (b) for the DOPC:SM:CHOL concentration 35:40:25.
(a)Experimentally derived phase plot from Veatch and Keller (Ref. 4). Black, white, and gray squares and circles are experimental points. White circles represent concentrations consisting of a uniform liquid phase, black circles denote coexisting liquid phases, gray squares denote coexisting gel, and liquid phases and white squares represent a uniform gel phase. Superimposed over the experimental plot are labels marking positions on the diagram that correspond to simulated DOPC:SM:CHOL order parameter plots shown in (b)–(k). At each represented concentration, order parameter field and the concentration field snapshots after are shown. CHOLs have been removed for clarity. The patterns reveal a separation into domains that is present in both fields at some concentrations. The scale of order parameter is shown in (l) and the scale of concentration field is shown in (m). The similarities between experiment and simulation are discussed in the text.
DOPC-SM-CHOL ternary lateral organization diagram. The shaded region indicates the presence of bimodality in the order parameter distributions. Dots indicate the average order parameter values, with coloring represented by the key to the right. Two overlapping dots that appear in the bimodal region represent the average order parameter of each peak.
Distribution plots of order parameter and concentration field for the DOPC:SM:CHOL concentrations labeled for the last snapshot of simulations.
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