No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.
Statistical physics of self-replication
1. C. W. Gardiner, Handbook of Stochastic Methods, 3rd ed. (Springer, 2003).
17. H. P. Rothbaum and H. M. Stone, J. Bacteriol. 81, 172 (1961).
24. F. C. Neidhardt, E. coli and Salmonella: Cellular and Molecular Biology (ASM Press, 1990), Vol. 1.
Article metrics loading...
Self-replication is a capacity common to every species of living thing, and simple physical intuition dictates that such a process must invariably be fueled by the production of entropy. Here, we undertake to make this intuition rigorous and quantitative by deriving a lower bound for the amount of heat that is produced during a process of self-replication in a system coupled to a thermal bath. We find that the minimum value for the physically allowed rate of heat production is determined by the growth rate, internal entropy, and durability of the replicator, and we discuss the implications of this finding for bacterial cell division, as well as for the pre-biotic emergence of self-replicating nucleic acids.
Full text loading...
Most read this month