Periodically repeating domain of interest.
Mouse endothelial cells shown in (a) (Ref. 32) appear approximately diamond shaped (cleft entrances are stained dark using silver nitrate). Based on this observation, the cleft entrance structure can be approximated by (b), or even further simplified to an infinitely repeating array of infinitely long parallel outflow slits as shown in (c). The simplified geometry (c) is characterized by only three parameters, namely, the cleft half-width , the cleft half-spacing , and the angle made between the clefts and the applied flow .
Streamlines in the vicinity of the intercellular cleft with domain dependent parameter values of , , , , and applied shear rates of (a) 0, (b) , (c) , and (d) . The horizontal dashed lines represent the interface between the glycocalyx and the free fluid.
Plots of the height of the stream tube captured by the cleft at a distance upstream of the cleft entrance against for various values of with fixed , , and .
Plots of evaluated at with fixed and for (a) fixed and various values of and (b) fixed and various values of .
Plots of evaluated at with fixed , , and for (a) fixed and various values of and (b) fixed and various values of .
Overview of ranges for nondimensional parameters.
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