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Label-free, all-electrical, in situ human epidermal growth receptor 2 detection
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View: Figures


Image of FIG. 1.
FIG. 1.

An optical micrograph of (a) PEMS-A, a long, wide PZT/glass PEMS with a long glass tip, and (b) PEMS-B, a long, wide PMN-PT/Sn PEMS used in this study.

Image of FIG. 2.
FIG. 2.

(a) Resonance frequency vs time of PEMS-A: PBS at , scFv immobilization at , PBS rinsing at , BSA blocking at , PBS rinsing at , and detection of Her2 at in background of BSA at and (b) the resonance spectra at , (after scFv immobilization), (after BSA blocking), and (after Her2 detection). Note that throughout the detection period, the shape of the resonance peak and the value remained constant.

Image of FIG. 3.
FIG. 3.

Resonance frequency shift vs time of PEMS-B at 5, 10, and of Her2 in a background of BSA. All results were the average of two independent detections with frequency shifts of , , and at , for 50, 10, and Her2 concentrations, respectively. The control experiment at of Her2 (dashed line) was obtained with a surrogate PMN-PT PEMS similar to PEMS-B. As can be seen, the surrogate PEMS at at of Her2.


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752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd
Scitation: Label-free, all-electrical, in situ human epidermal growth receptor 2 detection