Block diagram of the CW NIRI system. MCU is the microcontrol unit, DDS the direct digital synthesis, f1 and f2 the modulation frequencies, LD the laser diode, APD the avalanche photodiode, and DAQ the data acquisition.
(a) Schematic and (b) photograph of the collimator.
Detected light vs. OD values of neutral density filters.
Abridged general view of simulation experiment. The left part presents the composition of the mixed signal, the acquisition, and the off-line analysis before getting the result. The right part shows the results when the baseline of the mixed signal was set at 10 mV. The grey thin line and black thick line represent intensity changes during rest (no virtual stimuli) and task (virtual stimuli included) periods, respectively.
Time course of changes in hemodynamic parameters during arterial occlusion on a typical subject's arm. The red thin lines represent Δ[HbO2], while the blue thick lines represent Δ[Hb].
The schematic drawing of the head shows the arrangement of the probe with 2 sources (red circles) and 12 detectors (blue squares). The source-detector distance is 3 cm. The graphs represent Δ[HbO2] and Δ[Hb] traces of the block average responses obtained at 12 locations over the motor cortex for (a) the right-hand and (b) the left-hand finger-tapping measurement. The red thin line and blue thick line represent Δ[HbO2] and Δ[Hb] over the contralateral motor cortex, respectively, while the pink thin line and light blue thick line are Δ[HbO2] and Δ[Hb] for the ipsilateral motor cortex, respectively. The green horizontal bar in each graph indicates the task period.
Time traces of the averaged optical intensity during right-finger tapping. The blue thick line in all panels represents the averaged intensity changes of all segmented epochs at 785 nm for the channel of maximum contralateral response during the stimulation. The red thin line in panel (a) is the same signal measured at 850 nm. The black thin line in panel (b) is the intensity changes block-averaged with a false stimulation sequence during the rest periods at 785 nm for the same channel. The pink and orange thin lines in panel (c) represent the averaged intensities at 785 nm considering only odd or even stimuli, respectively. The light blue thin line in panel (d) represents the intensity changes during ipsilateral stimulation. The green vertical bars in all panels represent the times when the finger presses the button. The error bars are the standard errors.
Time-series maps of the dynamic changes of intensity over the motor cortex during right-hand (RH) and left-hand (LH) finger tapping. “Ipsi” and “Contra” indicate the hemispheres ipsilateral and contralateral to the stimulated hand, respectively. Time equal zero is the time when the finger presses the button.
Temporal resolution for different number of channels.
Performance parameters of the CW NIRI system.
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