- Conference date: 29 Aug - 1 Sep 1999
- Location: Kobe-Sanda (Japan)
This article reports comparison in the analysis of near-infrared (NIR) spectra of protein in control serum between generalized two-dimensional (2D) correlation spectroscopy and multivariate analysis, particularly, principal component analysis (PCA). NIR spectra were measured for human serum albumin (HSA) in the control serum with the final concentration range of 2.4–7.4 wt%. The synchronous and asynchronous 2D correlation spectra were generated from the concentration-dependent NIR spectral variations of HSA in the control serum. The same series of NIR spectra were also subjected to PCA. Comparison between the 2D correlation spectra and loadings plots for PCA has revealed that a power spectrum along the diagonal line on the synchronous spectrum resembles to the first loadings plots, while some slice spectra along particular wavenumbers of the asynchronous spectrum resemble the second loadings. The reasons why the synchronous and asynchronous spectra show good correspondence to the first and second loadings plots for PCA, respectively, are discussed in this paper.
- Multivariate analysis
- Spectrum analysis
- Nuclear magnetic resonance spectroscopy
Daniel Baumann, Mark G. Jackson, Peter Adshead, Alexandre Amblard, Amjad Ashoorioon, Nicola Bartolo, Rachel Bean, Maria Beltrán, Francesco de Bernardis, Simeon Bird, Xingang Chen, Daniel J. H. Chung, Loris Colombo, Asantha Cooray, Paolo Creminelli, Scott Dodelson, Joanna Dunkley, Cora Dvorkin, Richard Easther, Fabio Finelli, Raphael Flauger, Mark P. Hertzberg, Katherine Jones‐Smith, Shamit Kachru, Kenji Kadota, Justin Khoury, William H. Kinney, Eiichiro Komatsu, Lawrence M. Krauss, Julien Lesgourgues, Andrew Liddle, Michele Liguori, Eugene Lim, Andrei Linde, Sabino Matarrese, Harsh Mathur, Liam McAllister, Alessandro Melchiorri, Alberto Nicolis, Luca Pagano, Hiranya V. Peiris, Marco Peloso, Levon Pogosian, Elena Pierpaoli, Antonio Riotto, Uroš Seljak, Leonardo Senatore, Sarah Shandera, Eva Silverstein, Tristan Smith, Pascal Vaudrevange, Licia Verde, Ben Wandelt, David Wands, Scott Watson, Mark Wyman, Amit Yadav, Wessel Valkenburg and Matias Zaldarriaga
Data & Media loading...
Article metrics loading...