The present paper prepresents an attempt to summarize the different data needs in the context of interstellar space. The availability of future high spectral and angular resolution instruments reinforces the requirement of skilled data bases in a variety od domains. In addition to spectroscopic databases,
chemical kinetics data involving ion‐molecule, neutral‐neutral reaction,
dissociative recombination, photodissociation and photoionization cross sections are mentioned. We also refer to inelastic collision rate coefficients where atomic and molecular Hydrogen, Helium stand as perturbers. Finally we put forward the involvement of atomic and molecular databases into the efforts addressed by the perspective of International Virtual Observatories.