Computational Model of the Division Cycle of Caulobacter crescentus
- Conference date: 17–19 December 2007
- Location: Gold Coast, Queensland (Australia)
Based on published experimental evidence, we propose a molecular mechanism and a quantitative computational model for cell cycle control in Caulobacter crescentus. Our model predicts the detailed temporal dynamics of regulatory gene expression during the cell cycle and differentiation process of wild‐type cells as well as several mutant strains. Since many of the proteins involved in regulating the cell cycle of C.crescentus are conserved among other genera of α‐proteobacteria, the proposed mechanism may be applicable to these species.
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