- Conference date: 18–22 April 2010
- Location: Santa Fe, (New Mexico)
Interactions between laser radiation and photonic structures at elevated laser intensities give rise to the production of positive and negative ions from adsorbates. These new types of ion sources exhibit properties that are significantly different from conventional laser desorption ionization sources. In this contribution comparisons are made between matrix‐assisted laser desorption ionization (MALDI) of biomolecules with ion production from laser‐induced silicon microcolumn arrays (LISMA) and nanopost arrays (NAPA). The sharp increase of ion yields from the nanophotonic ion sources follow a power law behavior with an exponent of up to n≈7, whereas in the case of MALDI n≈5. The strong field enhancement in the vicinity of the columns and posts scales with their aspect ratio. Slender high aspect ratio posts show reduced laser fluence threshold for ionization. Posts with diameters at or below the thermal diffusion length demonstrate high surface temperatures due to the radial confinement of the deposited energy. As a consequence enhanced fragmentation, i.e., lower survival yield of the molecular ions is observed. The origin of protons in the ionization of adsorbates was identified as the entrapped residues of the solvent.
- Matrix assisted laser desorption ionization
- Ion sources
Daniel Baumann, Mark G. Jackson, Peter Adshead, Alexandre Amblard, Amjad Ashoorioon, Nicola Bartolo, Rachel Bean, Maria Beltrán, Francesco de Bernardis, Simeon Bird, Xingang Chen, Daniel J. H. Chung, Loris Colombo, Asantha Cooray, Paolo Creminelli, Scott Dodelson, Joanna Dunkley, Cora Dvorkin, Richard Easther, Fabio Finelli, Raphael Flauger, Mark P. Hertzberg, Katherine Jones‐Smith, Shamit Kachru, Kenji Kadota, Justin Khoury, William H. Kinney, Eiichiro Komatsu, Lawrence M. Krauss, Julien Lesgourgues, Andrew Liddle, Michele Liguori, Eugene Lim, Andrei Linde, Sabino Matarrese, Harsh Mathur, Liam McAllister, Alessandro Melchiorri, Alberto Nicolis, Luca Pagano, Hiranya V. Peiris, Marco Peloso, Levon Pogosian, Elena Pierpaoli, Antonio Riotto, Uroš Seljak, Leonardo Senatore, Sarah Shandera, Eva Silverstein, Tristan Smith, Pascal Vaudrevange, Licia Verde, Ben Wandelt, David Wands, Scott Watson, Mark Wyman, Amit Yadav, Wessel Valkenburg and Matias Zaldarriaga
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