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Acoustic response from adherent targeted contrast agents
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1.
1.Y. Tomita, P. B. Robinson, R. P. Tong, and J. R. Blake, “Growth and collapse of cavitation bubbles near a curved rigid boundary,” J. Fluid Mech.0022-1120 466, 259283 (2002).
http://dx.doi.org/10.1017/S0022112002001209
2.
2.K. Sato, Y. Tomita, and A. Shima, “Numerical-analysis of a gas bubble near a rigid boundary in an oscillatory pressure field,” J. Acoust. Soc. Am.0001-4966 95(5), 24162424 (1994).
http://dx.doi.org/10.1121/1.409851
3.
3.E. A. Brujan, K. Nahen, P. Schmidt, and A. Vogel, “Dynamics of laser-induced cavitation bubbles near an elastic boundary,” J. Fluid Mech.0022-1120 433, 251281 (2001).
4.
4.C. C. Church, “The effects of an elastic solid surface layer on the radial pulsations of gas-bubbles,” J. Acoust. Soc. Am.0001-4966 97(3), 15101521 (1995).
http://dx.doi.org/10.1121/1.412091
5.
5.S. K. Zhao, K. W. Ferrara, and P. A. Dayton, “Asymmetric oscillation of adherent targeted ultrasound contrast agents,” Appl. Phys. Lett.0003-6951 87(13), 134103 (2005).
http://dx.doi.org/10.1063/1.2061872
6.
6.J. P. Christiansen and J. R. Lindner, “Molecular and cellular imaging with targeted contrast ultrasound,” Proc. IEEE0018-9219 93(4), 809818 (2005).
7.
7.P. A. Schumann, J. P. Christiansen, R. M. Quigley, T. P. McCreery, R. H. Sweitzer, E. C. Unger, J. R. Lindner, and T. O. Matsunaga, “Targeted-microbubble binding selectively to GPIIb IIIa receptors of platelet thrombi,” Invest. Radiol.0020-9996, 37(11), 587593 (2002).
http://dx.doi.org/10.1097/00004424-200211000-00001
8.
8.H. Leong-Poi, J. Christiansen, A. L. Klibanov, S. Kaul, and J. R. Lindner, “Noninvasive assessment of angiogenesis by ultrasound and microbubbles targeted toalpha(v)-integrins,” Circulation0009-7322 107(3), 455460 (2003).
http://dx.doi.org/10.1161/01.CIR.0000044916.05919.8B
9.
9.S. Zhao, M. Borden, S. H. Bloch, D. Kruse, K. W. Ferrara, and P. A. Dayton, “Radiation-force assisted targeting facilitates ultrasonic molecular imaging,” Mol. Imaging1535-3508 3(3), 135148 (2004).
http://dx.doi.org/10.1162/1535350042380317
10.
10.J. J. Rychak, A. L. Klibanov, and J. A. Hossack, “Acoustic radiation force enhances targeted delivery of ultrasound contrast microbubbles: in vitro verification,” IEEE Trans. Ultrason. Ferroelectr. Freq. Control0885-3010 52(3), 421433 (2005).
http://dx.doi.org/10.1109/TUFFC.2005.1417264
11.
11.K. E. Morgan, J. S. Allen, P. A. Dayton, J. E. Chomas, A. L. Klibanov, and K. W. Ferrara, “Experimental and theoretical evaluation of microbubble behavior: Effect of transmitted phase and bubble size,” IEEE Trans. Ultrason. Ferroelectr. Freq. Control0885-3010 47(6), 14941509 (2000).
http://dx.doi.org/10.1109/58.883539
12.
12.B. Krasovitski and E. Kimmel, “Gas bubble pulsation in a semiconfined space subjected to ultrasound,” J. Acoust. Soc. Am.0001-4966 109(3), 891898 (2001).
http://dx.doi.org/10.1121/1.1346683
13.
13.G. M. Lanza, R. L. Trousil, K. D. Wallace, J. H. Rose, C. S. Hall, M. J. Scott, J. G. Miller, P. R. Eisenberg, P. J. Gaffney, and S. A. Wickline, “In vitro characterization of a novel, tissue-targeted ultrasonic contrast system with acoustic microscopy,” J. Acoust. Soc. Am.0001-4966 104(6), 36653672 (1998).
http://dx.doi.org/10.1121/1.423948
14.
14.P. A. Dayton, K. E. Morgan, A. L. S. Klibanov, G. Brandenburger, K. R. Nightingale, and K. W. Ferrara, “A preliminary evaluation of the effects of primary and secondary radiation forces on acoustic contrast agents,” IEEE Trans. Ultrason. Ferroelectr. Freq. Control0885-3010 44(6), 12641277 (1997).
http://dx.doi.org/10.1109/58.656630
15.
15.P. A. Dayton, K. E. Morgan, A. L. Klibanov, G. H. Brandenburger, and K. W. Ferrara, “Optical and acoustical observations of the effects of ultrasound on contrast agents,” IEEE Trans. Ultrason. Ferroelectr. Freq. Control0885-3010 46(1), 220232 (1999).
http://dx.doi.org/10.1109/58.741536
16.
16.J. S. Allen, D. E. Kruse, P. A. Dayton, and K. W. Ferrara, “Effect of coupled oscillations on microbubble behavior,” J. Acoust. Soc. Am.0001-4966 114(3), 16781690 (2003).
http://dx.doi.org/10.1121/1.1600721
17.
17.Y. T. Hu, S. P. Qin, T. Hu, K. W. Ferrara, and Q. Jiang, “Asymmetric oscillation of cavitation bubbles in a microvessel and its implications upon mechanisms of clinical vessel injury in shock-wave lithotripsy,” Int. J. Non-Linear Mech.0020-7462 40(2–3), 341350 (2005).
http://dx.doi.org/10.1016/j.ijnonlinmec.2004.06.007
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/content/asa/journal/jasa/120/6/10.1121/1.2364303
2006-10-23
2014-12-21

Abstract

In ultrasonic molecular imaging, encapsulated micron-sized gas bubbles are tethered to a blood vessel wall by targeting ligands. A challenging problem is to detect the echoes from adherent microbubbles and distinguish them from echoes from nonadherent agents and tissue. Echoes from adherent contrast agents are observed to include a high amplitude at the fundamental frequency, and significantly different spectral shape compared with free agents . Mechanisms for the observed acoustical difference and potential techniques to utilize these differences for molecular imaging are proposed.

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Scitation: Acoustic response from adherent targeted contrast agents
http://aip.metastore.ingenta.com/content/asa/journal/jasa/120/6/10.1121/1.2364303
10.1121/1.2364303
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