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1.
1. N. Davies, D. E. Weibel, P. Blenkinsopp, N. Lockyer, R. Hill, and J. C. Vickerman, Appl. Surf. Sci. 203, 223 (2003).
http://dx.doi.org/10.1016/S0169-4332(02)00631-1
2.
2. D. Touboul, F. Kollmer, E. Niehuis, A. Brunelle, and O. Laprevote, J. Am. Soc. Mass Spectrom. 16, 1608 (2005).
http://dx.doi.org/10.1016/j.jasms.2005.06.005
3.
3. D. Weibel, S. Wong, N. Lockyer, P. Blenkinsopp, R. Hill, and J. C. Vickerman, Anal. Chem. 75, 1754 (2003).
http://dx.doi.org/10.1021/ac026338o
4.
4. I. S. Gilmore, F. M. Green, and M. P. Seah, Surf. Interface Anal. 39, 817 (2007).
http://dx.doi.org/10.1002/sia.2596
5.
5. A. Carado, M. K. Passarelli, J. Kozole, J. E. Wingate, N. Winograd, and A. V. Loboda, Anal. Chem. 80, 7921 (2008).
http://dx.doi.org/10.1021/ac801712s
6.
6. E. J. Lanni, S. J. Dunham, P. Nemes, S. S. Rubakhin, and J. V. Sweedler, J. Am. Soc. Mass Spectrom. 25, 1897 (2014).
http://dx.doi.org/10.1007/s13361-014-0978-9
7.
7. J. S. Fletcher, S. Rabbani, A. Henderson, P. Blenkinsopp, S. P. Thompson, N. P. Lockyer, and J. C. Vickerman, Anal. Chem. 80, 9058 (2008).
http://dx.doi.org/10.1021/ac8015278
8.
8. D. F. Smith, E. W. Robinson, A. V. Tolmachev, R. M. Heeren, and L. Pasa-Tolic, Anal. Chem. 83, 9552 (2011).
http://dx.doi.org/10.1021/ac2023348
9.
9. J. C. Vickerman, Analyst 136, 2199 (2011).
http://dx.doi.org/10.1039/c1an00008j
10.
10. M. Andersson, M. R. Groseclose, A. Y. Deutch, and R. M. Caprioli, Nat. Methods 5, 101 (2008).
http://dx.doi.org/10.1038/nmeth1145
11.
11. L. S. Eberlin, D. R. Ifa, C. Wu, and R. G. Cooks, Angew. Chem. Int. Ed. 49, 873 (2010).
http://dx.doi.org/10.1002/anie.200906283
12.
12. L. Fornai et al., Anal. Bioanal. Chem. 404, 2927 (2012).
http://dx.doi.org/10.1007/s00216-012-6451-3
13.
13. M. Koestler, D. Kirsch, A. Hester, A. Leisner, S. Guenther, and B. Spengler, Rapid Commun. Mass Spectrom. 22, 3275 (2008).
http://dx.doi.org/10.1002/rcm.3733
14.
14. A. Zavalin, E. M. Todd, P. D. Rawhouser, J. Yang, J. L. Norris, and R. M. Caprioli, J. Mass Spectrom. 47, 1473 (2012).
http://dx.doi.org/10.1002/jms.3108
15.
15. A. Benninghoven, Z. Phys. 199, 141 (1967).
http://dx.doi.org/10.1007/BF01326023
16.
16.ToF-SIMS: Materials Analysis by Mass Spectrometry, 2nd ed., edited by J. C. Vickerman and D. Briggs ( IM Publications, Chichester, and Surface Spectra Ltd, Manchester, 2013).
17.
17. C. M. Mahoney, Mass Spectrom. Rev. 29, 247 (2010).
http://dx.doi.org/10.1002/mas.20233
18.
18. B. J. Garrison and Z. Postawa, Mass Spectrom. Rev. 27, 289 (2008).
http://dx.doi.org/10.1002/mas.20165
19.
19. C. M. Mahoney, S. V. Roberson, and G. Gillen, Anal. Chem. 76, 3199 (2004).
http://dx.doi.org/10.1021/ac035532n
20.
20. G. Gillen, A. Fahey, M. Wagner, and C. Mahoney, Appl. Surf. Sci. 252, 6537 (2006).
http://dx.doi.org/10.1016/j.apsusc.2006.02.235
21.
21. J. S. Fletcher, X. A. Conlan, N. P. Lockyer, and J. C. Vickerman, Appl. Surf. Sci. 252, 6513 (2006).
http://dx.doi.org/10.1016/j.apsusc.2006.02.213
22.
22. G. L. Fisher, A. M. Belu, C. M. Mahoney, K. Wormuth, and N. Sanada, Anal. Chem. 81, 9930 (2009).
http://dx.doi.org/10.1021/ac901587k
23.
23. A. Wucher, J. Cheng, L. Zheng, and N. Winograd, Anal. Bioanal. Chem. 393, 1835 (2009).
http://dx.doi.org/10.1007/s00216-008-2596-5
24.
24. L. L. Zheng, A. Wucher, and N. Winograd, J. Am. Soc. Mass Spectrom. 19, 96 (2008).
http://dx.doi.org/10.1016/j.jasms.2007.10.020
25.
25. J. Lovrić, J. D. Keighron, T. B. Angerer, L. Xianchan, P. Malmberg, J. S. Fletcher, and A. G. Ewing, Surf. Interface Anal. 46, 5 (2014).
http://dx.doi.org/10.1002/sia.5623
26.
26. S. Vaidyanathan, J. S. Fletcher, R. Goodacre, N. P. Lockyer, J. Micklefield, and J. C. Vickerman, Anal. Chem. 80, 1942 (2008).
http://dx.doi.org/10.1021/ac701921e
27.
27. P. M. Wehrli, E. Linberg, T. B. Angerer, A. E. Wold, J. Gottfries, and J. S. Fletcher, Surf. Interface Anal. 46, 173 (2014).
http://dx.doi.org/10.1002/sia.5505
28.
28. E. J. Lanni, R. N. Masyuko, C. M. Driscoll, J. T. Aerts, J. D. Shrout, P. W. Bohn, and J. V. Sweedler, Anal. Chem. 86, 9139 (2014).
http://dx.doi.org/10.1021/ac5020222
29.
29. J. S. Fletcher, N. P. Lockyer, S. Vaidyanathan, and J. C. Vickerman, Anal. Chem. 79, 2199 (2007).
http://dx.doi.org/10.1021/ac061370u
30.
30. J. S. Fletcher, A. Henderson, G. X. Biddulph, S. Vaidyanathan, N. P. Lockyer, and J. C. Vickerman, Appl. Surf. Sci. 255, 1264 (2008).
http://dx.doi.org/10.1016/j.apsusc.2008.05.253
31.
31. D. Breitenstein, C. E. Rommel, R. Mollers, J. Wegener, and B. Hagenhoff, Angew. Chem. Int. Ed. 46, 5332 (2007).
http://dx.doi.org/10.1002/anie.200604468
32.
32. J. Malm, D. Giannaras, M. O. Riehle, N. Gadegaard, and P. Sjövall, Anal. Chem. 81, 7197 (2009).
http://dx.doi.org/10.1021/ac900636v
33.
33. M. A. Robinson and D. G. Castner, Biointerphases 8, 15 (2013).
http://dx.doi.org/10.1186/1559-4106-8-15
34.
34. J. S. Fletcher, S. Rabbani, A. Henderson, N. P. Lockyer, and J. C. Vickerman, Rapid Commun. Mass Spectrom. 25, 925 (2011).
http://dx.doi.org/10.1002/rcm.4944
35.
35. S. Jung, M. Foston, U. C. Kalluri, G. A. Tuskan, and A. J. Ragauskas, Angew. Chem. Int. Ed. 51, 12005 (2012).
http://dx.doi.org/10.1002/anie.201205243
36.
36. J. Kokesch-Himmelreich, M. Schumacher, M. Rohnke, M. Gelinsky, and J. Janek, Biointerphases 8, 17 (2013).
http://dx.doi.org/10.1186/1559-4106-8-17
37.
37. M. A. Robinson, D. J. Graham, and D. G. Castner, Anal. Chem. 84, 4880 (2012).
http://dx.doi.org/10.1021/ac300480g
38.
38. A. J. Patkin, S. Chandra, and G. H. Morrison, Anal. Chem. 54, 2507 (1982).
http://dx.doi.org/10.1021/ac00251a023
39.
39. J. A. Whitby et al., Adv. Mater. Sci. Eng. 2012, 180437 (2012).
http://dx.doi.org/10.1155/2012/180437
40.
40. S. Koch, G. Ziegler, and H. Hutter, Anal. Bioanal. Chem. 405, 7161 (2013).
http://dx.doi.org/10.1007/s00216-013-6850-0
41.
41. T. B. Angerer and J. S. Fletcher, Surf. Interface Anal. 46, 198 (2014).
http://dx.doi.org/10.1002/sia.5444
42.
42. A. Wucher, J. Cheng, and N. Winograd, Anal. Chem. 79, 5529 (2007).
http://dx.doi.org/10.1021/ac070692a
43.
43. A. G. Shard, S. J. Spencer, S. A. Smith, R. Havelund, and I. S. Gilmore, “ The matrix effect in organic secondary ion mass spectrometry,” Int. J. Mass Spectrom. (in press).
http://dx.doi.org/10.1016/j.ijms.2014.06.027
44.
44. L. A. Giannuzzi and F. A. Stevie, Introduction to Focused Ion Beams: Instrumentation, Theory, Techniques, and Practice ( Springer, New York, 2005), pp. xiv, 357.
45.
45. C. Szakal, K. Narayan, J. Fu, J. Lefman, and S. Subramaniam, Anal. Chem. 83, 1207 (2011).
http://dx.doi.org/10.1021/ac1030607
46.
46. I. Yamada, J. Matsuo, N. Toyoda, and A. Kirkpatrick, Mater. Sci. Eng., R 34, 231 (2001).
http://dx.doi.org/10.1016/S0927-796X(01)00034-1
47.
47. S. Ninomiya, K. Ichiki, H. Yamada, Y. Nakata, T. Seki, T. Aoki, and J. Matsuo, Rapid Commun. Mass Spectrom. 23, 3264 (2009).
http://dx.doi.org/10.1002/rcm.4250
48.
48. A. G. Shard, P. J. Brewer, F. M. Green, and I. S. Gilmore, Surf. Interface Anal. 39, 294 (2007).
http://dx.doi.org/10.1002/sia.2525
49.
49. S. Rabbani, A. M. Barber, J. S. Fletcher, N. P. Lockyer, and J. C. Vickerman, Anal. Chem. 83, 3793 (2011).
http://dx.doi.org/10.1021/ac200288v
50.
50. J. S. Fletcher, S. Rabbani, A. M. Barber, N. P. Lockyer, and J. C. Vickerman, Surf. Interface Anal. 45, 273 (2013).
http://dx.doi.org/10.1002/sia.4874
51.
51. C. Bich, R. Havelund, R. Moellers, D. Touboul, F. Kollmer, E. Niehuis, I. S. Gilmore, and A. Brunelle, Anal. Chem. 85, 7745 (2013).
http://dx.doi.org/10.1021/ac4009513
52.
52. T. B. Angerer, P. Blenkinsopp, and J. S. Fletcher, “ High energy gas cluster ions for organic and biological analysis by time-of-flight secondary ion mass spectrometry,” Int. J. Mass Spectrom. (in press).
http://dx.doi.org/10.1016/j.ijms.2014.05.015
53.
53. A. Wucher, H. Tian, and N. Winograd, Rapid Commun. Mass Spectrom. 28, 396 (2014).
http://dx.doi.org/10.1002/rcm.6793
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Abstract

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) is a rapidly developing technique for the characterization of a wide range of materials. Recently, advances in instrumentation and sample preparation approaches have provided the ability to perform 3D molecular imaging experiments. Polyatomic ion beams, such as C, and gas cluster ion beams, often Ar (n = 500–4000), substantially reduce the subsurface damage accumulation associated with continued bombardment of organic samples with atomic beams. In this review, the capabilities of the technique are discussed and examples of the 3D imaging approach for the analysis of model membrane systems, plant single cell, and tissue samples are presented. Ongoing challenges for 3D ToF-SIMS imaging are also discussed along with recent developments that might offer improved 3D imaging prospects in the near future.

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