Skip to main content
banner image
No data available.
Please log in to see this content.
You have no subscription access to this content.
No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.
1.JS Fletcher, Cellular imaging with secondary ion mass spectrometry, Analyst 134, 2204 (2009).
2.P Sjovall, B Johansson, D Belazi, P Stenvinkel, B Lindholm, J Lausmaa and M Schalling, TOF-SIMS analysis of adipose tissue from patients with chronic kidney disease, Appl Surf Sci 255, 1177 (2008).
3.J Brison, DSW Benoit, S Muramoto, M Robinson, PS Stayton and DG Castner, ToF-SIMS imaging and depth profiling of HeLa cells treated with bromodeoxyuridine, Surf Interface Anal 43, 354 (2011).
4.CA Barnes, J Brison, M Robinson, DJ Graham, DG Castner and BD Ratner, Identifying individual cell types in heterogeneous cultures using secondary Ion mass spectrometry imaging with C60 etching and multivariate analysis, Anal Chem 84, 893 (2011).
5.YK Magnusson, P Friberg, P Sjovall, J Malm and Y Chen, TOF-SIMS analysis of lipid accumulation in the skeletal muscle of ob/ob mice, Obesity 16, 2745 (2008).
6.S Muramoto, DJ Graham, MS Wagner, TG Lee, DW Moon and DG Castner, ToF-SIMS analysis of adsorbed proteins: principal component analysis of the primary Ion species effect on the protein fragmentation patterns, J Phys Chem C 115, 24247 (2011).
7.M Dubey, J Brison, DW Grainger and DG Castner, Comparison of Bi+, Bi3+ and C60+ primary ion sources for ToF-SIMS imaging of patterned protein samples, Surf Interface Anal 43, 261 (2011).
8.N Graf, T Gross, T Wirth, W Weigel and WES Unger, Application of XPS and ToF-SIMS for surface chemical analysis of DNA microarrays and their substrates, Anal Bioanal Chem 393, 1907 (2009).
9.CY Lee, GM Harbers, DW Grainger, LJ Gamble and DG Castner, Fluorescence, XPS, and TOF-SIMS surface chemical state image analysis of DNA microarrays, J Am Chem Soc 129, 9429 (2007).
10.GL Fisher, AM Belu, CM Mahoney, K Wormuth and N Sanada, Three-dimensional time-of-flight secondary Ion mass spectrometry imaging of a pharmaceutical in a coronary stent coating as a function of elution time, Anal Chem 81, 9930 (2009).
11.A Belu, C Mahoney and K Wormuth, Chemical imaging of drug eluting coatings: combining surface analysis and confocal raman microscopy, J Controlled Release 126, 111 (2008).
12.LA Klerk, PYW Dankers, ER Popa, AW Bosman, ME Sanders, KA Reedquist and RMA Heeren, TOF-secondary Ion mass spectrometry imaging of polymeric scaffolds with surrounding tissue after in vivo implantation, Anal Chem 82, 4337 (2010).
13.CA Barnes, J Brison, R Michel, BN Brown, DG Castner, SF Badylak and BD Ratner, The surface molecular functionality of decellularized extracellular matrices, Biomaterials 32, 137 (2011).
14.A Gunnarsson, F Kollmer, S Sohn, F Hook and P Sjovall, Spatial-resolution limits in mass spectrometry imaging of supported lipid bilayers and individual lipid vesicles, Anal Chem 82, 2426 (2010).
15.S Muramoto, J Brison and DG Castner, Exploring the surface sensitivity of TOF-secondary Ion mass spectrometry by measuring the implantation and sampling depths of Bin and C60 ions in organic films, Anal Chem 84, 365 (2012).
16.ME Kurczy, PD Piehowsky, D Willingham, KA Molyneaux, ML Heien, N Winograd and AG Ewing, Nanotome cluster bombardment to recover spatial chemistry after preparation of biological samples for SIMS imaging, J Am Soc Mass Spectrom 21, 833 (2010).
17.ME Kurczy, PD Piehowski, SA Parry, M Jiang, G Chen, AG Ewing and N Winograd, Which is more important in bioimaging SIMS experiments-the sample preparation or the nature of the projectile?, Appl Surf Sci 255, 1298 (2008).
18.S Chandra, Imaging intracellular elemental distribution and ion fluxes in cultured cells using ion microscopy: a freeze-fracture methodology, J Microsc 144, 15 (1986).
19.TP Roddy, DM Cannon, SG Ostrowski, N Winograd and AG Ewing, Identification of cellular sections with imaging mass spectrometry following freeze fracture, Anal Chem 74, 4020 (2002).
20.AM Piwowar, NP Lockyer and JC Vickerman, Salt effects on Ion formation in desorption mass spectrometry: an investigation into the role of alkali chlorides on peak suppression in time-of-flight-secondary Ion mass spectrometry, Anal Chem 81, 1040 (2009).
21.EA Jones, NP Lockyer and JC Vickerman, Depth profiling brain tissue sections with a 40 keV C-60(+) primary ion beam, Anal Chem 80, 2125 (2008).
22.ESF Berman, SL Fortson, KD Checchi, L Wu, JS Felton, KJJ Wu and KS Kulp, Preparation of single cells for imaging/profiling mass spectrometry, J Am Soc Mass Spectrom 19, 1230 (2008).
23.H Nygren, C Eriksson, P Malmberg, H Sahlin, L Carlsson, J Lausmaa and P Sjovall, A cell preparation method allowing subcellular localization of cholesterol and phosphocholine with imaging TOF-SIMS, Colloids Surf B Biointerfaces 30, 87 (2003).
24.J Malm, D Giannaras, MO Riehle, N Gadegaard and P Sjovall, Fixation and drying protocols for the preparation of cell samples for time-of-flight secondary Ion mass spectrometry analysis, Anal Chem 81, 7197 (2009).
25.MK Passarelli and N Winograd, Characterizing in situ glycerophospholipids with SIMS and MALDI methodologies, Surf Interface Anal 43, 269 (2011).
26.D Breitenstein, CE Rommel, J Stolwijk, J Wegener and B Hagenhoff, The chemical composition of animal cells reconstructed from 2D and 3D ToF-SIMS analysis, Appl Surf Sci 255, 1249 (2008).
27.D Breitenstein, CE Rommel, R Mollers, J Wegener and B Hagenhoff, The chemical composition of animal cells and their intracellular compartments reconstructed from 3D mass spectrometry, Angew Chem Int Ed 46, 5332 (2007).
28.S Chandra, WA Ausserer and GH Morrison, Evaluation of matrix effects in ion microscopic analysis in freeze-fractured, freeze-dried cultured cells, J Microsc 148, 223 (1987).
29.M Fartmann, C Kriegeskotte, S Dambach, A Wittig, W Sauerwein and HF Arlinghaus, Quantitative imaging of atomic and molecular species in cancer cultures with TOF-SIMS and Laser-SNMS, Appl Surf Sci 231, 428 (2004).
30.I Lanekoff, ME Kurczy, KL Adams, J Malm, R Karlsson, P Sjovall and AG Ewing, An in situ fracture device to image lipids in single cells using ToF-SIMS, Surf Interface Anal 43, 257 (2011).
31.J Clerc, C Fourre and P Fragu, SIMS microscopy: methodology, problems and perspectives in mapping drugs and nuclear medicine compounds, Cell Biol Int 21, 619 (1997).
32.E Kellenberger, Cryotechniques in biological electron microscopy, edited by RA Steinbrecht and K Zierold (Springer-Verlag, Berlin, 1987).
33.JS Fletcher, S Rabbani, A Henderson, NP Lockyer and JC Vickerman, Three-dimensional mass spectral imaging of HeLa-M cells - sample preparation, data interpretation and visualisation, Rapid Commun Mass Spectrom 25, 925 (2011).
34.JF Frisz, K Lou, HA Klitzing, WP Hanafin, V Lizunov, RL Wilson, KJ Carpenter, R Kim, ID Hutcheon, J Zimmerberg, PK Weber and ML Kraft, Direct chemical evidence for sphingolipid domains in the plasma membranes of fibroblasts, Proc Natl Acad Sci USA 110, E613 (2013).
35.CM Mahoney, AJ Fahey, G Gillen, C Xu and JD Batteas, Temperature-controlled depth profiling of poly(methyl methacrylate) using cluster secondary ion mass spectrometry. 2. Investigation of sputter-induced topography, chemical damage, and depolymerization effects, Anal Chem 79, 837 (2007).
36.CM Mahoney, AJ Fahey and G Gillen, Temperature-controlled depth profiling of poly(methyl methacrylate) using cluster secondary ion mass spectrometry. 1. Investigation of depth profile characteristics, Anal Chem 79, 828 (2007).
37.AM Piwowar, JS Fletcher, J Kordys, NP Lockyer, N Winograd and JC Vickerman, Effects of cryogenic sample analysis on molecular depth profiles with TOF-secondary Ion mass spectrometry, Anal Chem 82, 8291 (2010).
38.PD Piehowski, ME Kurczy, D Willingham, S Parry, ML Heien, N Winograd and AG Ewing, Freeze-etching and vapor matrix deposition for ToF-SIMS imaging of single cells, Langmuir 24, 7906 (2008).
39.KB Lewis and BD Ratner, Observation of surface rearrangement of polymers using ESCA, J Colloid Interface Sci 159, 77 (1993).
40.PK Ratner BDW, AS Hoffman, MA Kelly and LH Scharpen, Radiation-grafted hydrogels for biomaterial applications as studied by the ESCA technique, J Appl Polym Sci 22, 643 (1978).
41.S Rabbani, JS Fletcher, NP Lockyer and JC Vickerman, Exploring subcellular imaging on the buncher-ToF J105 3D chemical imager, Surf Interface Anal 43, 380 (2011).
42.J Moller, A Beumer, D Lipinsky and HF Arlinghaus, Introduction of a cryosectioning-ToF-SIMS instrument for analysis of non-dehydrated biological samples, Appl Surf Sci 252, 6709 (2006).
43.I Lanekoff, ME Kurczy, R Hill, JS Fletcher, JC Vickerman, N Winograd, P Sjovall and AG Ewing, Time of flight mass spectrometry imaging of samples fractured in situ with a spring-loaded trap System, Anal Chem 82, 6652 (2010).
44.A Wittig, M Wiemann, M Fartmann, C Kriegeskotte, HF Arlinghaus, K Zierold and W Sauerwein, Preparation of cells cultured on silicon wafers for mass spectrometry analysis, Microsc Res Tech 66, 248 (2005).
45.AM Piwowar, S Keskin, MO Delgado, K Shen, JJ Hue, I Lanekoff, AG Ewing and N Winograd, C60-ToF SIMS imaging of frozen hydrated HeLa cells, Surf Interface Anal 45, 302 (2013).
46.J Brison, S Muramoto and DG Castner, ToF-SIMS depth profiling of organic films: a comparison between single-beam and dual-beam analysis, J Phys Chem C 114, 5565 (2010).
47.N Tahallah, A Brunelle, S De La Porte and O Laprevote, Lipid mapping in human dystrophic muscle by cluster-time-of-flight secondary ion mass spectrometry imaging, J Lipid Res 49, 438 (2008).
48.MK Passarelli and N Winograd, Lipid imaging with time-of-flight secondary ion mass spectrometry (ToF-SIMS), Biochim Biophys Acta 1811, 976 (2011).
49.AFM Altelaar, I Klinkert, K Jalink, RPJ De Lange, RAH Adan, RMA Heeren and SR Piersma, Gold-enhanced biomolecular surface imaging of cells and tissue by SIMS and MALDI mass spectrometry, Anal Chem 78, 734 (2005).
50.DG Castner and BD Ratner, Biomedical surface science: foundations to frontiers, Surf Sci 500, 28 (2002).
51.I Lanekoff, ME Kurczy, R Hill, JS Fletcher, JC Vickerman, N Winograd, P SjöVall and AG Ewing, Time of flight mass spectrometry imaging of samples fractured in situ with a spring-loaded trap system, Anal Chem 82, 6652 (2010).
52.MA Robinson, DJ Graham and DG Castner, ToF-SIMS depth profiling of cells: z-correction, 3D imaging, and sputter rate of individual NIH/3T3 fibroblasts, Anal Chem 84, 4880 (2012).
53.JS Fletcher, NP Lockyer and JC Vickerman, Developments in molecular SIMS depth profiling and 3D imaging of biological systems using polyatomic primary ions, Mass Spectrom Rev 30, 142 (2011).
54.AG Sostarecz, DM Cannon, CM Mcquaw, S Sun, AG Ewing and N Winograd, Influence of molecular environment on the analysis of phospholipids by time-of-flight secondary Ion mass spectrometry, Langmuir 20, 4926 (2004).
55.B Vaezian, CR Anderton and ML Kraft, Discriminating and imaging different phosphatidylcholine species within phase-separated model membranes by principal component analysis of TOF-secondary Ion mass spectrometry images, Anal Chem 82, 10006 (2010).
56.DS Mantus, BD Ratner, BA Carlson and JF Moulder, Static secondary ion mass spectrometry of adsorbed proteins, Anal Chem 65, 1431 (1993).
57.JB Lhoest, MS Wagner, CD Tidwell and DG Castner, Characterization of adsorbed protein films by time of flight secondary ion mass spectrometry, J Biomed Mater Res 57, 432 (2001).<432::AID-JBM1186>3.0.CO;2-G
58.XA Conlan, NP Lockyer and JC Vickerman, Is proton cationization promoted by polyatomic primary ion bombardment during time-of-flight secondary ion mass spectrometry analysis of frozen aqueous solutions?, Rapid Commun Mass Spectrom 20, 1327 (2006).
59.IA Wojciechowski, U Kutliev, S Sun, C Szakal, N Winograd and BJ Garrison, Emission of ionic water clusters from water ice films bombarded by energetic projectiles, Appl Surf Sci 231–232, 72 (2004).
60.IA Wojciechowski, S Sun, C Szakal, N Winograd and BJ Garrison, Ion emission from water Ice Due to energetic particle bombardment†, J Phys Chem A 108, 2993 (2004).

Data & Media loading...


Full text loading...


Access Key

  • FFree Content
  • OAOpen Access Content
  • SSubscribed Content
  • TFree Trial Content
752b84549af89a08dbdd7fdb8b9568b5 journal.articlezxybnytfddd