Surface modification of gold–carbon nanotube nanohybrids under the influence of near-infrared laser exposure
(Color online) Experimental setup outlining the laser path and sample position presented as (a) schematic and (b) digital image.
(Color online) Functionalization, capture, and labeling process. (1) Condensation of carboxylic acids and amino-modified ssDNA leading to biofunctionalized SWNTs. (2) Capture of csDNA and hybridization with ssDNA into dsDNA on SWNT sidewalls. (3) Addition of GNP labels onto functional thiolated end of dsDNA-SWNTs.
Transmission electron micrographs demonstrating labeling of biofunctionalized SWNTs with GNPs before and after exposure to NIR. (a) 10 nm, (b) 30 nm, (c) 60 nm, (d) SWNT-GNP10 nm, (e) SWNT-GNP30 nm, (f) SWNT-GNP60 nm, (g) SWNT-GNP10 nm post NIR, (h) SWNT-GNP30 nm post NIR, and (i) SWNT-GNP60 nm post NIR.
(Color online) Representative heating kinetic profiles (change in temperature over time) for SWNT solutions irradiated with 4.5 W laser for 5 min and monitored during cooling for an additional 5 min.
(Color online) Overview of the biomolecular functionalization and capture process to form hybrid SWNT-GNP nanostructures, which are further modified upon NIR laser exposure. (1) Binding of biomolecules onto SWNT surface. (2) Hybridization of complementary target binding sequences. (3) Addition of GNPs. (4) Detachment of GNPs via NIR laser exposure.
Summary of surface charge of nanomaterials prior to and after NIR exposure.
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