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Cover: This micrograph shows a prototype of a silicon chip containing an integrated x-ray sensor (orange) and refrigerator. Tunnel junctions composed of an insulating layer between a metal and a superconductor form the heart of the refrigerator and are located at each corner of the square sensor. To learn how circuits made from such tunnel junctions can work as thermometers and solid-state refrigerators, turn to the article by Jukka Pekola, Robert Schoelkopf, and Joel Ullom on page 41. (Photo courtesy of Joel Ullom and Anna Clark.)