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Method for trapping and manipulating nanoscale objects in solution

Appl. Phys. Lett. 86, 093109 (2005); doi:10.1063/1.1872220

Published 25 February 2005

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Adam E. Cohen
Department of Physics, Stanford University, Stanford, California 94305

W. E. Moerner
Department of Chemistry, Stanford University, Stanford, California 94305
We present a device that allows a user to trap a single nanoscale object in solution at ambient temperature, and then to position the trapped object with nanoscale resolution. This anti-Brownian electrophoretic trap (ABEL trap) works by monitoring the Brownian motion of the particle (via fluorescence microscopy), and then applying a feedback voltage to the solution so that the electrophoretic drift exactly cancels the Brownian motion. The ABEL trap works on any object that can be imaged optically and that acquires a charge in water. The ABEL trap is noninvasive, is gentle enough to handle biological molecules, and can trap objects far smaller than can be trapped with laser tweezers. Our proof-of-principle device can trap fluorescent polystyrene nanospheres with diameters down to 20  nm. ©2005 American Institute of Physics
History: Received 4 October 2004; accepted 7 January 2005; published 25 February 2005
Permalink: http://link.aip.org/link/?APPLAB/86/093109/1
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KEYWORDS and PACS

Keywords
PACS
  • 87.80.Fe
    Micromanipulators (biological techniques/biomedical engineering)
  • 72.20.Jv
    Charge carriers: generation, recombination, lifetime, and trapping (semiconductors/insulators)
  • 87.83.+a
    Biomedical applications of nanotechnology
  • YEAR: 2005

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PUBLICATION DATA

ISSN:
0003-6951 (print)   1077-3118 (online)
Publisher:
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REFERENCES (7)
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  2. P. R. C. Gascoyne and J. V. Vykoukal, Proc. IEEE 92, 22 (2004).
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