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Living tissue under treatment of cold plasma atmospheric jet

Appl. Phys. Lett. 93, 181501 (2008); doi:10.1063/1.3020223

Published 4 November 2008

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A. Shashurin,1 M. Keidar,1 S. Bronnikov,1 R. A. Jurjus,2 and M. A. Stepp2
1Department of Mechanical and Aerospace Engineering, School of Engineering and Applied Science, The George Washington University, Washington, District of Columbia 20052, USA
2Department of Anatomy and Regenerative Biology, George Washington University Medical School, The George Washington University, Washington, District of Columbia 20052, USA
The interaction of the cold atmospheric plasma jet with fibroblast cells was studied. Plasma jet was initiated in the helium flow blowing through the syringe by application of high ac voltage to the discharge electrodes. The plasma jet had a length of 5  cm and a diameter of 1.5–2  mm in ambient air. Treatment of cells with plasma jet resulted in decreasing of cell migration rate, cell detachment, and appearance of “frozen” cells, while treatment with helium flow (no plasma) resulted in appearance of frozen cells only. A variety of cellular responses was explained by different intensities of treatment. ©2008 American Institute of Physics
History: Received 29 September 2008; accepted 16 October 2008; published 4 November 2008
Permalink: http://link.aip.org/link/?APPLAB/93/181501/1
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KEYWORDS and PACS

Keywords
PACS
  • 87.85.-d
    Biomedical engineering
  • 52.75.-d
    Plasma devices
  • 52.77.Fv
    Applications of high-pressure, high-current plasmas
  • 87.17.Jj
    Cell locomotion; chemotaxis
  • YEAR: 2008

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PUBLICATION DATA

ISSN:
0003-6951 (print)   1077-3118 (online)
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