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Concurrent droplet charging and sorting by electrostatic actuation

Biomicrofluidics 3, 044102 (2009); doi:10.1063/1.3250303

Published 13 October 2009

Byungwook Ahn, Kangsun Lee, Romain Louge, and Kwang W. Oh
Department of Electrical Engineering, nanobio Sensors and MicroActuators Learning Lab (SMALL), University at Buffalo, The State University of New York at Buffalo, Buffalo, New York 14260, USA
This paper presents a droplet-based microfluidic device for concurrent droplet charging and sorting by electrostatic actuation. Water-in-oil droplets can be charged on generation by synchronized electrostatic actuation. Then, simultaneously, the precharged droplets can be electrostatically steered into any designated laminar streamline, thus they can be sorted into one of multiple sorting channels one by one in a controlled fashion. In this paper, we studied the size dependence of the water droplets under various relative flow rates of water and oil. We demonstrated the concurrent charging and sorting of up to 600 droplets/s by synchronized electrostatic actuation. Finally, we investigated optimized voltages for stable droplet charging and sorting. This is an essential enabling technology for fast, robust, and multiplexed sorting of microdroplets, and for the droplet-based microfluidic systems. ©2009 American Institute of Physics
History: Received 25 August 2009; accepted 25 September 2009; published 13 October 2009
Permalink: http://link.aip.org/link/?BIOMGB/3/44102/1
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KEYWORDS and PACS

Keywords
PACS
  • 85.85.+j
    Micro- and nano-electromechanical systems (MEMS/NEMS) and devices
  • 07.10.Cm
    Micromechanical devices and systems
  • 87.80.Ek
    Mechanical and micromechanical techniques (biophysical research methods)
  • 47.55.D-
    Drops and bubbles
  • 47.85.Np
    Fluidics (applied)
  • YEAR: 2009

PUBLICATION DATA

ISSN:
1932-1058 (online)
Publisher:
AIP is a member of CrossRef AIP

REFERENCES (27)
View in Separate Window/Tab
  1. S. Y. Teh, R. Lin, L. H. Hung, and A. P. Lee, Lab Chip 8, 198 (2008). [MEDLINE]
  2. B. T. Kelly, J. C. Baret, V. Taly, and A. D. Griffiths, Chem. Commun. (Cambridge) 2007, 1773.
  3. V. Taly, B. T. Kelly, and A. D. Griffiths, ChemBioChem 8, 263 (2007). [MEDLINE]
  4. H. Song, D. L. Chen, and R. F. Ismagilov, Angew. Chem., Int. Ed. 45, 7336 (2006). [MEDLINE]
  5. A. Huebner, S. Sharma, M. Srisa-Art, F. Hollfelder, J. B. Edel, and A. J. Demello, Lab Chip 8, 1244 (2008). [MEDLINE]
  6. M. Joanicot and A. Ajdari, Science 309, 887 (2005). [MEDLINE]
  7. V. Cristini and Y. C. Tan, Lab Chip 4, 257 (2004). [Inspec] [MEDLINE]
  8. Y. C. Tan, J. S. Fisher, A. I. Lee, V. Cristini, and A. P. Lee, Lab Chip 4, 292 (2004). [MEDLINE]
  9. Y. C. Tan, Y. L. Ho, and A. P. Lee, Microfluid. Nanofluid. 4, 343 (2008).
  10. C. -H. Yang, Y. -S. Lin, K. -S. Huang, Y. -C. Huang, E. -C. Wang, J. -Y. Jhong, and C. -Y. Kuo, Lab Chip 9, 145 (2009). [MEDLINE]
  11. C. -Y. Lee, Y. -H. Lin, and G. -B. Lee, Microfluid. Nanofluid. 6, 599 (2009).
  12. C. N. Baroud, M. R. de Saint Vincent, and J. P. Delville, Lab Chip 7, 1029 (2007). [MEDLINE]
  13. T. Franke, A. R. Abate, D. A. Weitz, and A. Wixforth, Lab Chip 9, 2625 (2009). [MEDLINE]
  14. D. R. Link, E. Grasland-Mongrain, A. Duri, F. Sarrazin, Z. D. Cheng, G. Cristobal, M. Marquez, and D. A. Weitz, Angew. Chem., Int. Ed. 45, 2556 (2006). [MEDLINE]
  15. K. Ahn, C. Kerbage, T. P. Hunt, R. M. Westervelt, D. R. Link, and D. A. Weitz, Appl. Phys. Lett. 88, 024104 (2006).
  16. H. M. Shapiro, Practical Flow Cytometry, 4th ed. (Wiley, New York, 2003).
  17. G. Durack and J. P. Robinson, Emerging Tools for Single-Cell Analysis: Advances in Optical Measurement Technologies (Wiley, New York, 2000).
  18. M. Eisenstein, Nature (London) 441, 1179 (2006). [MEDLINE]
  19. D. Huh, W. Gu, Y. Kamotani, J. B. Grotberg, and S. Takayama, Physiol. Meas. 26, R73 (2005). [MEDLINE]
  20. O. Raccurt, J. Berthier, P. Clementz, M. Borella, and M. Plissonnier, J. Micromech. Microeng. 17, 2217 (2007).
  21. Y. C. Tan, V. Cristini, and A. P. Lee, Sens. Actuators B 114, 350 (2006).
  22. N. Dubash and A. J. Mestel, Phys. Fluids 19, 072101 (2007). [ISI]
  23. Y. H. Zhan, J. Wang, N. Bao, and C. Lu, Anal. Chem. 81, 2027 (2009).
  24. D. W. Lee and Y. H. Cho, Sens. Actuators B 124, 84 (2007).
  25. J. Gao, X. F. Yin, and Z. L. Fang, Lab Chip 4, 47 (2004). [Inspec] [MEDLINE]
  26. S. W. Lee and Y. C. Tai, Sens. Actuators, A 73, 74 (1999).
  27. F. Malloggi, S. A. Vanapalli, H. Gu, D. van den Ende, and F. Mugele, J. Phys.: Condens. Matter 19, 462101 (2007).





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