Preliminary Development and Engineering Evaluation of a Novel Cricothyrotomy Device
Cricothyrotomy is one of the procedures used to ventilate patients with upper airway blockage. This paper examines the most regularly used and preferred cricothyrotomy devices on the market, suggests ...
Cricothyrotomy is one of the procedures used to ventilate patients with upper airway blockage. This paper examines the most regularly used and preferred cricothyrotomy devices on the market, suggests ...
Design Improvements and In Vitro Testing of an Implantable Muscle Energy Converter for Powering Pulsatile Cardiac Assist Devices
Harnessing skeletal muscle for circulatory support would improve on current blood pump technologies by eliminating infection-prone drivelines and cumbersome transcutaneous energy transmission systems....
Harnessing skeletal muscle for circulatory support would improve on current blood pump technologies by eliminating infection-prone drivelines and cumbersome transcutaneous energy transmission systems....
Design of a Cooling Guide Catheter for Rapid Heart Cooling
J. Med. Devices -- September 2010 -- Volume 4, Issue 3, 035001 (8 pages)
doi:10.1115/1.4002063
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Cardiovascular disease is the leading cause of death in the United States. Despite decades of care path improvements approximately 30% of heart attack victims die within 1 year after their first heart attack. Animal testing has shown that mild hypothermia, reducing tissue temperatures by 2–4°C, has the potential to save heart tissue that is not adequately perfused with blood. This paper describes the design of a cooling guide catheter that can provide rapid, local cooling to heart tissue during emergency angioplasty. Using standard materials and dimensions found in typical angioplasty guide catheters, a closed-loop cooling guide catheter was developed. Thermal fluid modeling guided the interior geometric design. After careful fabrication and leak testing, a mock circulatory system was used to measure catheter cooling capacity. At blood analog flow rates ranging from 20 ml/min to 70 ml/min, the corresponding cooling capacity varied almost linearly from 20 W to 45 W. Animal testing showed 18 W of cooling delivered by the catheter can reduce heart tissue temperatures rapidly, approximately 3° in 5 min in some locations. Future animal testing work is needed to investigate if this cooling effect can save heart tissue.
©2010 American Society of Mechanical Engineers
| History: | Received 8 March 2010; revised 1 June 2010; published 31 August 2010 | |
| doi: | http://dx.doi.org/10.1115/1.4002063 | |
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