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Dynamic position and force measurement for multiple optically trapped particles using a high-speed active pixel sensor

Rev. Sci. Instrum. 80, 103704 (2009); doi:10.1063/1.3202381

Published 7 October 2009

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M. Towrie,1 S. W. Botchway,1 A. Clark,2 E. Freeman,2 R. Halsall,2 A. W. Parker,1 M. Prydderch,2 R. Turchetta,2 A. D. Ward,1 and M. R. Pollard1
1Department of Photon Science, Lasers for Science Facility, Rutherford Appleton Laboratory, Science and Technology Facilities Council, Didcot OX11 0QX, United Kingdom
2Department of Technology, Rutherford Appleton Laboratory, Science and Technology Facilities Council, Didcot OX11 0QX, United Kingdom
A high frame rate active pixel sensor designed to track the position of up to six optically trapped objects simultaneously within the field of view of a microscope is described. The sensor comprises 520×520  pixels from which a flexible arrangement of six independent regions of interest is accessed at a rate of up to 20 kHz, providing the capability to measure motion in multiple micron scale objects to nanometer accuracy. The combined control of both the sensor and optical traps is performed using unique, dedicated electronics (a field programmable gate array). The ability of the sensor to measure the dynamic position and the forces between six optically trapped spheres, down to femtonewton level, is demonstrated paving the way for application in the physical and life sciences. ©2009 American Institute of Physics
History: Received 1 May 2009; accepted 20 July 2009; published 7 October 2009
Permalink: http://link.aip.org/link/?RSINAK/80/103704/1
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KEYWORDS and PACS

Keywords
PACS
  • 07.07.Df
    Sensors (chemical, optical, electrical, movement, gas, etc.); remote sensing
  • 42.79.Pw
    Imaging detectors and sensors
  • 84.30.Sk
    Pulse and digital circuits
  • YEAR: 2009

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PUBLICATION DATA

ISSN:
0034-6748 (print)   1089-7623 (online)
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