Vir. J. Bio. Phys. Res. / Volume 20 / Issue 3 / CANCER PHYSICS

Hairpin DNA coated gold nanoparticles as intracellular mRNA probes for the detection of tyrosinase gene expression in melanoma cells

Source: Chem. Commun. 46, 5557 (2010); doi:10.1039/c001969k

Issue Date: 1 August 2010

ABSTRACT

^* Full Text: Access via Source Journal Abstract

PUBLICATION DATA

ISSN:

1553-9628 (online)

Publisher:

RSC

S. Reese Harry
Department of Chemistry, Vanderbilt University, Station B351822, Nashville, TN 37235, USA. david.wright@vanderbilt.edu

Donna J. Hicks

Katayoun I. Amiri

David W. Wright

Anew intracellular mRNA imaging probe has been developed that incorporatesthiol-terminated hairpin oligonucleotides covalently bound to the surface of citrate-cappedgold nanoparticles. The hairpin DNA-coated gold nanoparticles (hAuNPs) positively identifiestyrosinase mRNA in cultured melanoma cells. ©2010

Permalink:

http://dx.doi.org/10.1039/c001969k

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Hairpin DNA coated gold nanoparticles as intracellular mRNA probes for the detection of tyrosinase gene expression in melanoma cells

Source: Chem. Commun. 46, 5557 (2010); doi:10.1039/c001969k