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High voltage-derived enhancement of electric conduction in nanogap devices for detection of prostate-specific antigen

Source: Appl. Phys. Lett. 97, 033701 (2010); doi:10.1063/1.3464160

Published 20 July 2010

KEYWORDS and PACS
Keywords
PACS
  • 87.85.Rs
    Nanotechnologies - applications in biomedical engineering
  • 87.85.fk
    Biosensors for smart prosthetics
  • YEAR: 2010
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PUBLICATION DATA
ISSN:
1553-9628 (online)
Publisher:
AIP is a member of CrossRef AIP
Hyung Ju Park,1,2 Young Shik Chi,2 Insung S. Choi,1 and Wan Soo Yun1,2
1Department of Chemistry, Molecular-Level Interface Research Center, KAIST, Daejeon 305-701, Republic of Korea
2Center for Nanoscience and Quantum Metrology, Korea Research Institute of Standards and Science (KRISS), Daejeon 305-600, Republic of Korea
We report a simple method of enhancing electric conductance in nanogap devices without any additional treatments, such as silver-enhancing process. The low electric conductance after selective immobilization of biofunctionalized gold nanoparticles in the gap region was greatly enhanced by repeated I-V scans at relatively high voltage ranges of −5 to 5 V, which was attributed to the formation of a new conduction pathway across the gap. The higher conduction state of the nanogap device showed a very stable I-V curve, which was used as an excellent measure of the existence of prostate-specific antigen. ©2010 American Institute of Physics
History: Received 13 May 2010; accepted 19 June 2010; published 20 July 2010
Permalink: http://link.aip.org/link/?APPLAB/97/033701/1

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