Vir. J. Bio. Phys. Res. / Volume 20 / Issue 3 / INSTRUMENTATION DEVELOPMENT

Real-time, step-wise, electrical detection of protein molecules using dielectrophoretically aligned SWNT-film FET aptasensors

Source: Lab Chip 10, 2052 (2010); doi:10.1039/c005276k

Issue Date: 1 August 2010

ABSTRACT

^* Full Text: Access via Source Journal Abstract

PUBLICATION DATA

ISSN:

1553-9628 (online)

Publisher:

RSC

Taechang An
Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), San 31, Hyoja-dong, Nam-gu, Pohang, Kyungbuk, 790-784, Korea. limmems@postech.ac.kr

Ki Su Kim

Sei Kwang Hahn

Geunbae Lim

Aptamerfunctionalized addressable SWNT-film arrays between cantilever electrodes were successfully developedfor biosensor applications. Dielectrophoretically aligned SWNT suspended films made possiblehighly specific and rapid detection of target proteins with alarge binding surface area. Thrombin aptamer immobilized SWNT-film FET biosensorresulted in a real-time, label-free, and electrical detection of thrombinmolecules down to a concentration of ca. 7 pM witha step-wise rapid response time of several seconds. ©2010

Permalink:

http://dx.doi.org/10.1039/c005276k

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Real-time, step-wise, electrical detection of protein molecules using dielectrophoretically aligned SWNT-film FET aptasensors

Source: Lab Chip 10, 2052 (2010); doi:10.1039/c005276k